Inherited human cPLA2α deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction
J. Clin. Invest. David H. Adler, et al. 118:2121 doi:10.1172/JCI30473 [
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Figure 1Arachidonic cascade initiated by cPLA
2α.
P450, cytochrome P450; LOX, lipoxygenase. cPLA
2α reaction is in red, and other enzymatic reactions are in blue.