p21^Cip1 modulates arterial wound repair through the stromal cell–derived factor-1/CXCR4 axis in mice
J. Clin. Invest. Michelle Olive, et al. 118:2050 doi:10.1172/JCI31244 [Go to this article.]

Figure 1
Accelerated proliferation and apoptosis in vitro in p21^–/– VSMCs. (A) Increased growth rate in p21^–/– VSMCs (blue triangles) compared with p21^+/+ VSMCs (yellow squares) (n = 3; *P < 0.05, ***P < 0.001). (B) Increased percentage of apoptotic cells in p21^–/– VSMCs (blue bars) induced with 0, 375, or 750 μM of H₂O₂ compared with p21^+/+ VSMCs (yellow bars) (n = 3; ***P < 0.001 versus corresponding p21^+/+ group).