Ablation of GalNAc-4-sulfotransferase-1 enhances reproduction by altering the carbohydrate structures of luteinizing hormone in mice
J. Clin. Invest. Yiling Mi, et al. 118:1815 doi:10.1172/JCI32467 [
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Figure 3LH, T, and FSH levels in WT and
GalNAc-4-ST1–/– male mice.
Serum was collected from 8- to 10-week-old male WT and
GalNAc-4-ST1–/– mice. Levels of LH, T, and FSH were determined by radioimmunoassay. In each case, the difference in mean values was significant. (
A)
P = 0.0001, LH (squares, triangles);
P = 0.04, T (inverted triangles, diamonds). (
B)
P = 0.026, FSH. (
C)
P = 0.009, LH 5 days following castration.