Bim-mediated deletion of antigen-specific CD8+ T cells in patients unable to control HBV infection
J. Clin. Invest. A. Ross Lopes, et al. 118:1835 doi:10.1172/JCI33402 [
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Figure 4Direct ex vivo rescue of HBV-specific CD8
+ T cells from patients with CHB.
Representative flow cytometry plots and cumulative data (below) indicating direct ex vivo frequencies of HBV-specific CD8
+ T cells in patients with chronic infection as detected following stimulation with viral peptide with and without treatment with the pancaspase inhibitor zVAD-fmk.